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RESEARCH

My research focuses on pediatric gastroenterology, especially on functional gastrointestinal disorders. Childhood constipation is the main research area and the other area I work most is functional abdominal pain. In addition, to these two main areas my other work includes other functional gastrointestinal disorders such as aerophagia, and rumination syndrome. Gastrointestinal disorders in very young children is also another of my research interest. I also work on areas such as inflammatory bowel disease, and liver disease in children as well.

Dr. Shaman Rajindrajith
MBBS, MD, FRCPCH, PHD ( Amsterdam )

PEER REVIEW PUBLICATIONS IN JOURNALS

01

Sexual abuse in illegally adopted children.
de Silva DG, Jayawardena PP, Rajeendrajith S , Gunaratne M.
Ceylon Medical Journal 1997;42(1):44.

02

An interventional study to monitor weight gain in infants using a home based complementary food recipe and a hand blender.
de Silva D.G.H, Rajindrajith S, Pathmeswaran A, Karunasekara W.
The Ceylon Medical Journal 2007; 52 (3): 79-83.

03

Advanced hepatic fibrosis and cirrhosis due to non-alcoholic fatty liver disease in Sri Lankan children: A preliminary report.
Rajindrajith S
, Dassanayake A, Hewavisenthi J, de Silva H.J.
Hepatology International 2008;2: 209-12.

04

Helicobacter pylori infection in children.
Rajindrajith S, Devanarayana NM, HJ de Silva.
Sri Lanka Journal of Child Health, 2009; 38: 86-88.

05

Constipation and functional faecal retention in a group of school children in a district in Sri Lanka.
Rajindrajith S
, Devanarayana NM, Mettananda S, Perera P, Jasmin S, Karunarathna U, Adhihetty D, Goonewardena
Sri Lanka Journal of Child Health, 2009; 38: 60-64.

06

Recurrent abdominal pain in children.
Devanarayana NM, Rajindrajith S, de Silva HJ.
Indian Pediatrics 2009; 46(5): 389-401

07

Helicobacter pylori infection in children.
Rajindrajith S, Devanrayana NM, de Silva HJ.
The Saudi Journal of Gastroenterology 2009; 15: 86-94.

08

Neonatal mortality in Sri Lanka: Timing, causes and distribution.
Rajindrajith S, Mettananda S, Adihetti D, Goonawardana R, Devanarayana NM.
The Journal of Maternal-Fetal and neonatal Medicine 2009; 22: 791-796.

09

Hospital-based study of the severity and economic burden associated with rotavirus diarrhea in Sri Lanka.
Nilmini Chandrasena, Shaman Rajindrajith, Ahmed Kamruddin, Arunachalam Pathmeswaran, Osamu Nakagomi.
Journal of Pediatric Infectious Diseases 2009; 4: 379-386

10

Constipation in children: diagnosis and management.
Rajindrajith S
, Devanarayana NM.
Sri Lanka Journal of Child Health, 2009; 38: 127-135.

11

Prevalence and risk factors for non-alcoholic fatty liver disease among adults in an urban Sri Lankan population.
Dassanayake AS, Kasturiratne A, Rajindrajith S, Kalubowila U, Chakrawarthi S, De Silva AP, Makaya M, Mizoue T, Kato N, Wickremasinghe AR, de Silva HJ.
Journal of Gastroenterology and Hepatology. 2009 Jul;24(7):1284-8.

12

Association between constipation and stressful life events in a cohort of Sri Lankan children and adolescents.
Devanarayana NM, Rajindrajith S.
Journal of Tropical Pediatrics 2010;56:144-48.

13

Rotavirus with multiple emerging genotypes in Sri Lanka.
Ahmed K, Batuwanthudawe R, Chandrasena TGAN, Mitui MT, Rajindrajith S, Galagoda G, Pun SB, Uchida R, Kunii O, Moji K, Abesinghe N, Nishizono A, Nakagomi O.
Achieves of Virology 2010;155:71-75

14

Prevalence of inflammatory bowel disease in two districts of Sri Lanka: a hospital based survey.
Niriella MA, de Silva AP, Dayaratne HGAK, Ariyasinghe M, Navarathna NMM, Peiris SKR, Samarasekara DN, Satharasinghe RL, Rajindrajith S, Dassanayake AS, Wickramasinghe AR, de Silva HJ.
BMC Gastroenterology 2010;10:32.

15

Constipation-associated and nonretentive fecal incontinence in children and adolescents: an epidemiological survey in Sri Lanka.
Rajindrajith S, Devanarayana NM, Benninga MA.
Journal of Pediatric Gastroenterology and Nutrition 2010;51:472-76.

16

Prevalence of functional gastrointestinal diseases in a cohort of Sri Lankan adolescents: comparison between Rome II and Rome III criteria.
Devanarayana NM, Adhikari C, Pannala W, Rajindrajith S.
Journal of Tropical Pediatrics
2011;57:34-39.

17

Bowel habits and behaviours related to defecation in 10 to 16 year olds: impact of socio-economic characteristics and emotional stress.
Devanarayana NM, Rajindrajith S.
Journal of Pediatric Gastroenterology and Nutrition 2011;52: 569-73.

18

Constipation in children: Novel insight into epidemiology, pathophysiology and management
Rajindrajith S, Devanarayana NM.
Journal of Neurogastroenterology and Motility 2011.;17:35-47.

19

Constipation during and after the civil war in Sri Lanka: a paediatric study.
Rajindrajith S, Mettananda S, Devanarayana NM.
Journal of Tropical Pediatrics 2011;57:439-43

20

Prevalence of acanthosis nigricans in an urban population in Sri Lanka and its utility to detect metabolic syndrome.
Dassanayake AS, Kasturiratne A, Niriella MA, Kalubowila U, Rajindrajith S, De Silva AP, Kato N, wickramasinghe AR, De Silva HJ.
BMC Research Notes 2011Jan 28;4(1):25.

21

Abdominal pain predominant functional gastrointestinal diseases in children and adolescents: symptomatology and association with stress
Devanarayana NM, Mettananda S, Liyanarachchi C, Nanayakkara N, Mendis N, Perera N, Rajindrajith S
Journal of Paediatric Gastroenterology and Nutrition. 2011 Dec;53(6):659-65.

22

Aerophagia among Sri Lankan school children: epidemiological patterns and symptom characteristics.
Devanarayana NM, Rajindrajith S.
Journal of Paediatric Gastroenterology and Nutrition 2012;54:516-20.

23

Rotavirus with multiple emerging genotypes in Sri Lanka.
Ahmed K, Batuwanthudawe R, Chandrasena TGAN, Mitui MT, Rajindrajith S, Galagoda G, Pun SB, Uchida R, Kunii O, Moji K, Abesinghe N, Nishizono A, Nakagomi O.
Achieves of Virology 2010;155:71-75

24

Prevalence of inflammatory bowel disease in two districts of Sri Lanka: a hospital based survey.
Niriella MA, de Silva AP, Dayaratne HGAK, Ariyasinghe M, Navarathna NMM, Peiris SKR, Samarasekara DN, Satharasinghe RL, Rajindrajith S, Dassanayake AS, Wickramasinghe AR, de Silva HJ.
BMC Gastroenterology 2010;10:32.

25

Constipation-associated and nonretentive fecal incontinence in children and adolescents: an epidemiological survey in Sri Lanka.
Rajindrajith S, Devanarayana NM, Benninga MA.
Journal of Pediatric Gastroenterology and Nutrition 2010;51:472-76.

26

Prevalence of functional gastrointestinal diseases in a cohort of Sri Lankan adolescents: comparison between Rome II and Rome III criteria.
Devanarayana NM, Adhikari C, Pannala W, Rajindrajith S.
Journal of Tropical Pediatrics
2011;57:34-39.

27

Bowel habits and behaviours related to defecation in 10 to 16 year olds: impact of socio-economic characteristics and emotional stress.
Devanarayana NM, Rajindrajith S.
Journal of Pediatric Gastroenterology and Nutrition 2011;52: 569-73.

28

Constipation in children: Novel insight into epidemiology, pathophysiology and management
Rajindrajith S, Devanarayana NM.
Journal of Neurogastroenterology and Motility 2011.;17:35-47.

29

Constipation during and after the civil war in Sri Lanka: a paediatric study.
Rajindrajith S, Mettananda S, Devanarayana NM.
Journal of Tropical Pediatrics 2011;57:439-43

30

Prevalence of acanthosis nigricans in an urban population in Sri Lanka and its utility to detect metabolic syndrome.
Dassanayake AS, Kasturiratne A, Niriella MA, Kalubowila U, Rajindrajith S, De Silva AP, Kato N, wickramasinghe AR, De Silva HJ.
BMC Research Notes 2011Jan 28;4(1):25.

31

Rumination syndrome in children and adolescent: a school survey assessing prevalence and symptomatology.
Rajindrajith S, Devanarayana NM, Perera BJC.
BMC Gastroenterology 2012;12:163 (doi 10:1186/1471-230X-12-163.)

32

Ultrasonographic assessment of liquid gastric emptying and antral motility according to the subtypes of irritable bowel syndrome in children.
Devanarayana NM, Rajindrajith S, Bandara C, Shashiprabha G, Benninga MA.
Journal of Paediatric Gastroenterology and Nutrition 2013;56:443-8.

33

Functional gastrointestinal diseases in children: facing the rising tide.
Rajindrajith S, Devanarayana NM.
Journal of Gastroenterology and Hepatology 2013; 28: 28-10.
Journal of Paediatric Gastroenterology and Nutrition 2013;56:443-8.

34

Gastric emptying and antral motility parameters in children with functional dyspepsia: association with symptom severity.
Devanarayana NM, Rajindrajith S, Perera MS, Nishanthani SW, Benninga MA.
Journal of Gastroenterology and Hepatology 2013;28:1161-6

35

Functional gastrointestinal disease in children: Stepping out of the box.
Rajindrajith S, Devanarayana NM.
Sri Lanka Journal of Child Health 2013;42:65-69.

36

Clinical profile and difficulties in diagnosis of central nervous system infections in adult patients in a tertiary care hospital.
Ranawaka UK, Rajindrajith S, Perera KV, Dassanayake KM, Premaratne BA, de Silva HJ.
Ceylon Medical Journal 2013;58:26-28.

37

Primary care management of chronic constipation in Asia: The ANMA chronic constipation tool.
Gwee KA, Ghoshal UC, Gonlachanvit S, Chua AS, Myung SJ, Rajindrajith S, Patcharatrakul T, Choi MG, Wu JC, Chen MH, Gong XR, Lu CL, Chen CL, Pratap N, Abraham P, Hou XH, Ke M, Ricaforte-Campos JD, Syam AF, Abdullah M.
J Nerougastroenterology and Motility 2013;19:149-60.

38

Quality of life and somatic symptoms in children with constipation: a school based study.
Rajindrajith S, Devanarayana NM, Weerasooriya L, Hathagoda W, Benninga NM.
Journal of Pediatrics 2013;163:1069-72.

39

Human Bocavirus in patients with encephalitis, Sri Lanka, 2009-2010.
Mori D, Ranawaka U, Yamada K, Rajindrajith S, Miya K, Perera HK, Matsumato T, Dassanayake M, Mitui MT, Mori H, Nishizono A, Soderlund-Venermo M, Ahmed K.
Emerging Infectious Disease2013;19:1859-62.

40

Association between child maltreatment and constipation: a school based survey using Rome III criteria.
Rajindrajith S, Devanarayana NM. Lakmini C, Subasinghe V, de Silva DG, Benninga MA.
Journal of Pediatric Gastroenterology and Nutriton 2014;58:486-90.

41

Incidence of inflammatory bowel disease in Gampaha district: details of the Sri Lankan component of the Asia-Pacific Crohns and Colitis Epidemiology Study.
Kasturiratne A, Mufeena MN, Mettananda KC, Fernandopulle N, Rajindrajith S, Waraketiya PR, Weerasinghe KS, Ranaweera A, Hewavisenthi SJ, de Silva AP, de Silva HJ.
Ceylon Medical Journal 2014;1:16-8.

42

Obesity and functional gastrointestinal diseases in children.
Rajindrajith S, Devanarayana NM, Benninga MA.
Journal of Neurogastroenterology and Motility 2014; 20:414-16.

43

Association between functional gastrointestinal diseases and exposure to abuse in children.
Devanarayana NM, Rajindrajith S, Perera MS, Nishanthini S, Karunanayake A, Benninga MA.
Journal of Tropical Pediatrics 2014 July 23 [epub ahead of print]

44

Quality of life and healthcare consultation in 13-18 year olds with abdonminal pain predominant functional gastrointestinal diseases.
Devanarayana NM, Rajindrajith S, Benninga MA.
BMC Gastroenterology 2014 Aug 21:14(1):150

45

Constipation in children: From misty to understanding (Dr. Stella de Silva Memorial Oration).
Rajindrajith S 
Sri Lanka Journal of Child Health 2014;43 (3):121-41.

46

Transplacental transfer of dengue.
Ekanayake CD, Padumadasa S, Premaratha R, Rajindrajith S, Samaranayake WW.
Ceylon Medical Journal 2014;59(4):145-6.

47

Micronutrient status and its relationship with nutritional status in preschool children in urban Sri Lanka.
Marasinghe E, Chackrewarthy S, Abesena C, Rajindrajith S.
Asia Pacific Journal of Clinical Nutrition 2015;24: 144-51

48

Childhood functional abdominal pain: mechanisms and management.
Korterink J, Devanarayana NM, Rajindrajith S, Vlieger A, Benninga MA.
Nature Review Gastroenterology and Hepatology 2015;12:159-71.

49

Small circular single stranded DNA vrial genomes in unexplained cases of human encephalitis, diarrhea and untreated sewage.
Phan TG, Mori D, Deng X, Rajindrajith S, Ranawaka U, Fan Ng TF, Burdardo-Rivera F, Orlandi P, Ahmed K, Delvart E.
Virology 2015;31:498-104.

50

Irritable bowel syndrome in children and adolescents in Asia: A systematic review and meta-analysis of the epidemiology.
Devanarayana NM, Rajindrajith S, Pathmeswaran A, Abegunasekara C, Gunawardena NK, Benninga MA.
Journal of Pediatric Gastroenterology and Nutrition 2015 (epub ahead of print).

51

Abdominal pain predominant functional gastrointestinal diseases in adolescent Nigerians.
Udoh E, Devanarayana NM, Rajindrajith S, Meremikwu M, Benninga MA.
Journal of Pediatric Gastroenterology and Nutrition. October 2015 (Accepted for Publication 28/09/2015

52

Fecal incontinence in adolescents is associated with child abuse, somatization and poor health related quality of life.
Rajindrajith S, Devanarayana NM, Benninga MA.
Journal of Pediatric Gastroenterology and Nutrition. October 2015 (Accepted for Publication 08/10/2015)

53

Abdominal migraine in children: association between gastric motility paramenters and clinical characttteriiistics.
Devanarayana NM, Rajindrajith S, Benninga MA.
BMC Gastroenterology 2016 Feb 29;16(1):26

54

Prevalence of Functional Defecation Disorders in Children: A Systematic Review and Meta-Analysis.
Koppen IJN, Vriesman MH, Saps M, Rajindrajith S, Shi X, van Etten-Jamaludin FS, Di Lorenzo C, Benninga MA, Tabbers MM.
J Pediatr. 2018 Apr 12.

55

Functional gastrointestinal diseases and psychological maladjustment, personality traits and quality of life.
Ranasinghe N, Devanarayana NM, Rajindrajith S, Perera MS, Nishanthinie S, Warnakulasuriya T, de Zoysa PT.
BMC Gastroenterol. 2018 Feb 27;18(1):33.

56

Functional abdominal pain disorders in children.
Rajindrajith S, Zeevenhooven J, Devanarayana NM, Perera BJC, Benninga MA.
Expert Rev Gastroenterol Hepatol. 2018 Apr;12(4):369-390.

57

Non-alcoholic fatty liver disease and its associations among adolescents in an urban, Sri Lankan community.
Rajindrajith S, Pathmeswaran A, Jayasinghe C, Kottahachchi D, Kasturiratne A, de Silva ST, Niriella MA, Dassanayake AS, de Silva AP, de Silva HJ.
BMC Gastroenterol. 2017 Nov 29;17(1):135.

58

Randomized Controlled Clinical Trial on Value of Domperidone in Functional Abdominal Pain in Children.
Karunanayake A, Devanarayana NM, de Silva A, Gunawardena S, Rajindrajith S.
J Pediatr Gastroenterol Nutr. 2018 May;66(5):725-731.

59

Prevalence and risk factors for functional constipation in adolescent Nigerians.
Udoh EE, Rajindrajith S, Devanarayana NM, Benninga MA.
Arch Dis Child. 2017 Sep;102(9):841-844.

60

Constipation and Constipation-predominant Irritable Bowel Syndrome: A Comparative Study Using Rome III Criteria.
Rajindrajith S, Devanarayana NM, Benninga MA.
J Pediatr Gastroenterol Nutr. 2017 May;64(5):679-684.

61

Psychological maladjustment and quality of life in adolescents with constipation.
Ranasinghe N, Devanarayana NM, Benninga MA, van Dijk M, Rajindrajith S.
Arch Dis Child. 2017 Mar;102(3):268-273.

62

Childhood constipation as an emerging public health problem.
Rajindrajith S, Devanarayana NM, Crispus Perera BJ, Benninga MA.
World J Gastroenterol. 2016 Aug 14;22(30):6864-75.

63

Prevalence and risk factors of functional constipation in adolescents Nigerians.
Udoh EE, Rajindrajith S, Devanarayana NM, Benninga MA.
Arch Dis Child 2017;102:841-44.

64

Aerophagia in adolescents is associated with exposure to adverse life events and psychological maladjustment.
Rajindrajith S, Hettige S, Gulegoda I, Jayawirckrama N, de Silva SC, Samarakoon HK, de Silva RL, Abeyagunawardena S, Devanarayana NM.
Neurogastroenterol Motil 2018;30(3). Doi:10.111/nmo.13224.

65

Randomized controlled clinical trial on value of domperidone in functional abdominal pain disorders in children.
Karunanayake A, Devanarayana NM, de Silva A, Gunawardena S, Rajindrajith S.
J Pediatr Gastroenterol Nutr 2018;66:725-31.

66

Non-alcoholic fatty liver disease and its associations among adolescents in an unban, Sri Lankan community.
Rajindrajith S, Pathmeswaran A, Jayasinghe C, Kottahachchi D, Kasturitatne A, de Silva SR, Niriella MA, Dassanayake AS, de Silva AP, de Silva HJ.
BMC Gastroenterol 2017;17:135. Doi.10. 1186/s12876-017-0677-7.

67

Functional abdominal pain disorders in children.
Rajindrajith S, Zeevenjooven J, Devanarayana NM, Perera BJC, Benninga MA.
Expert Rev Gastroenterol Hepatol 2018;12:369-390.

68

Functional gastrointestinal diseases and psychological maladjustment, personality traints and quality of life.
Rajasinghe N, Devanarayana NM, Rajindraijth S, Perera MS, Nishanthini S, Warnakulasooriya T, de Zoysa PT.
BMC Gastroenterol 2018;28:33. Doi: 10.1186/s12876-018-0760-8.

69

Prevalence of functional defecation disorders in children: A systematic review and meta-analysis.
Koppen IJN, Vriesman MH, Saps M, Rajindrajith S, Shi X, van Etten-Jamaludin FS, Di Lorenzo C, Benninga MA, Tabbers MM.
J Pediatr 2018;198:121-130.

70

Irritable bowel syndrome in children: Current knowledge, challenges and opportunities.
Devanarayana NM, Rajindraijth S.
World J Gastroenterol 2018;24:2211-35.

71

Human-porcine reassortant rotavirus generated by multiple reassortment events in a Sri Lankan child with diarrhoea.
Yahiro T, Takaki M, Chandrasena TGAN, Rajindrajith S, Iha H, Ahmed K.
Infect Genet Evol 2018;65:170-186.

72

Paucity of interlobular bile ducts in multidrug-resistant P-glycoprotein 3 (MDR3) deficiency.
Vij M, Valamparampil J, Shanmugum N, Reddy SM, Rajindrajith S, Rela M.
Int J Surg Pathol 2019;27:343-47.

73

Epidemiology of paediatric constipation in Indonesia and its association with exposure to stressful life events.
Oswari H, Alatas FS, Hegar B, Cheng W, Pramadyani A, Benninga MA, Rajindraijth S.
BMC Gastroenterol 2018;18:146

74

Delayed or not delayed? This is the question in Indian children with constipation.
Rajindrajith S, Devanarayana NM, Benninga MA.
Indian J Gastroenterol 2018;37:385-87.

75

Association between functional abdominal pain disorders and asthma in adolescents: A cross sectional study.
Kumari, MV, Devanarayana NM, Amarasiri L, Rajindraijth S.
World J Clin Cases 2018;6:944-51.

76

Autonomic function and gastric motility in children with functional abdominal pain disorders.
Karunanayake A, Rajindrajith S, de Silva HA, Gunawardena S, Devanarayana NM.
World J Gastroenterol 2019;25:95-108.

77

Quality of life in children with functional constipation: A systematic review and meta-analysis.
Vriesman MH, Rajindraijth S, Koppen IJN, van Etten- Jamaludin FS, van Dijk M, Tabbers MM, Benninga MA.
J Pediatr 2019. Pii:Soo22-3476(19)30823-6.

78

Functional constipation in infancy and dearly childhood: epidemiology, risk factors, and healthcare consultation.
Walter AW, Hovenkamp A, Devanarayana NM, Solanga R, Rajindrajith S, Benninga MA.
BMC Pediatr 2019;19:285.

79

Functional abdominal pain disorders in adolescents in Indonesia and their association with family related stress.
Oswari H, Alatas FS, Hegar B, Cheng W, Pramadyani A, Benninga MA, Rajindrajith S.
BMC Pediatr 2019;19:342.

80

Epidemiology of functional abdominal pain disorders and functional defecation disorders in adolescents in Curacao.
Zeevenhooven J, van der Heijden S, Devanarayana NM, Rajindrajith S, Benninga MA.
J Pediatir 2020;70: e71-76.

81

A core outcome set for clinical trials in pediatrc functional abdominal pain disorders.
Zeevanhooven J, Rexwinkel R, Henegouwen V, Krishnan U, Vandenplas Y, Strisciuglio C, Staiano A, Devanarayana NM, Rajindrajith S, Benninga MA, Tabbers MM.
Consensus group on Outcome Measures Maade in Pediatric Enteral Nutrition Clinical Trial Working Group. J Pediatr 2020;221:115-22.

Book Chapters

1

Chapter 6 – Clinical evaluation of children with constipation: History and physical examination.
Invited book chapter. Rajindrajith S, Devanarayana NM. In: Constipation in children.
Editor Ramon NN. Nova Publishers. 2013.

2

Chapter 1 – Prevalence and international perspectives of functional gastrointestinal disease in children.
Invited book chapter. Rajindrajith S, Devanarayana NM, Benninga MA. In: Psychosocial aspects of children with gastroenterological conditions.
Editor Martin C, and Dovey T. Oxford University Press, Oxford, UK.2014.

3

Chapter- Defecation disorders in children: Invited book chapter.
Rajindrajith S, Devanarayana NM, Benninga MA. In Pediatric Gastroenterology Hepatology, and Nutrition.
Editors, Guwandalini S, Barr P, Dhawan A. Springer Press, London UK 2016.

4

Chapter 38- Neurogastroenterology and motility disorders in pediatric population. Invited book chapter.
Rajindrajith S, Devanarayana NM, Chanpong A, Thapar N. In Clinical and Basic Neurogastroenterology and Motility.
Editors Rao SSC, Lee YY, and Ghoshal UC. Academic Press, Oxford, UK. 2020.

5

Functional dyspepsia (my 10-year-old patient is complaining of post-prandial upper abdominal pain. How should I proceed?).
Shaman Rajindrajith, and Niranga Devanarayana. Pediatric Gastroenterology.
Editor Pankaj Vohra. 2020.

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